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1

Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces

Silvia Gazzin, Nathalie Strazielle, Charlotte Schmitt, Michelle Fevre-Montange, J. Donald Ostrow, Claudio Tiribelli, Jean-François Ghersi-Egea

Journal:

The Journal of Comparative Neurology

Year:

2008

Language:

english

File:

PDF, 824 KB

english, 2008

2

Localization of Drug-Metabolizing Enzyme Activities to Blood-Brain Interfaces and Circumventricular Organs

J. F. Ghersi-Egea, B. Leninger-Muller, G. Suleman, G. Siest, A. Minn

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 911 KB

english, 1994

3

Molecular characterization of circumventricular organs and third ventricle ependyma in the rat: potential markers for periventricular tumors

Alexandru Szathmari, Jacques Champier, Jean-François Ghersi-Egea, Anne Jouvet, Chantal Watrin, Anne Wierinckx, Michelle Fèvre Montange

Journal:

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

4

Conséquences de l'hypoxie sur la production de radicaux superoxydes par les neurones en culture

JL Daval, J Oillet, JF Ghersi-Egea, P Vert

Journal:

Archives de Pédiatrie

Year:

1995

File:

PDF, 78 KB

1995

5

Les plexus choroïdes : une interface dynamique entre sang et liquide cephalo-rachidien

Mutin, M., Ghersi-Egea, J.F., Strazielle, N.

Journal:

Year:

2005

Language:

french

File:

PDF, 549 KB

french, 2005

6

Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus

Jean-Francois Ghersi-Egea, Nathalie Strazielle

Journal:

Microscopy Research and Technique

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

7

Rat choroid plexuses contain myeloid progenitors capable of differentiation toward macrophage or dendritic cell phenotypes

Serge Nataf, Nathalie Strazielle, Eric Hatterer, Guy Mouchiroud, Marie-Françoise Belin, Jean-François Ghersi-Egea

Journal:

Year:

2006

Language:

english

File:

PDF, 1.52 MB

english, 2006

8

Quantitative measurement of cerebral cytochrome P-450 by second derivative spectrophotometry

J.F. Ghersi-Egea, B. Walther, A. Minn, G. Siest

Journal:

Journal of Neuroscience Methods

Year:

1987

Language:

english

File:

PDF, 582 KB

english, 1987

9

Fate of Cerebrospinal Fluid-Borne Amyloid β-Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries

J.-F. Ghersi-Egea, P. D. Gorevic, J. Ghiso, B. Frangione, C. S. Patlak, J. D. Fenstermacher

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 669 KB

english, 1996

10

Factors affecting delivery of antiviral drugs to the brain

Nathalie Strazielle, Jean-François Ghersi-Egea

Journal:

Reviews in Medical Virology

Year:

2005

Language:

english

File:

PDF, 328 KB

english, 2005

11

Organotypic rat brain culture as in vivo-like model system

Stefan Fennrich, Heike Stier, Karl-Josef Föhr, David Ray, Jean-François Ghersi-Egea, Burkhard Schlosshauer

Journal:

Methods in Cell Science

Year:

1996

Language:

english

File:

PDF, 2.08 MB

english, 1996

12

NADPH:cytochrome P-450(c) reductase: Biochemical characterization in rat brain and cultured neurons and evolution of activity during development

J. F. Ghersi-Egea, A. Minn, J. L. Daval, Z. Jayyosi, V. Arnould, H. Souhaili-El Amri, G. Siest

Journal:

Neurochemical Research

Year:

1989

Language:

english

File:

PDF, 513 KB

english, 1989

13

Changes of cerebral gamma glutamyltransferase activities after treatment with exogenous inducers

J. F. Ghersi-Egea, A. Minn, G. Siest

Journal:

Neurochemical Research

Year:

1987

Language:

english

File:

PDF, 297 KB

english, 1987

14

Regional brain variations of cytochrome oxidase activity and motor coordination in Lurcher mutant mice

C. Strazielle, P. Krémarik, J.-F. Ghersi-Egea, R. Lalonde

Journal:

Experimental Brain Research

Year:

1998

Language:

english

File:

PDF, 517 KB

english, 1998

15

Regional acetylcholinesterase activity and its correlation with behavioral performances in 15-month old transgenic mice expressing the human C99 fragment ofAPP

M. Dumont, R. Lalonde, J.-F. Ghersi-Egea, K. Fukuchi, C. Strazielle

Journal:

Journal of Neural Transmission

Year:

2006

Language:

english

File:

PDF, 317 KB

english, 2006

16

In Vivo Study of the Elimination from Rat Brain of an Intracerebrally Formed Xenobiotic Metabolite, 1-Naphthyl-β-D-Glucuronide

Brigitte Leininger, Jean-François Ghersi-Egea, Gérard Siest, Alain Minn

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 618 KB

english, 1991

17

Impairment of blood–cerebrospinal fluid barrier properties by retrovirus-activated T lymphocytes: reduction in cerebrospinal fluid-to-blood efflux of prostaglandin E2

Seng Thuon Khuth, Nathalie Strazielle, Pascale Giraudon, Marie-Françoise Belin, Jean-François Ghersi-Egea

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

18

Active transport at the blood-CSF barrier contributes to manganese influx into the brain

Charlotte Schmitt, Nathalie Strazielle, Pierre Richaud, Alexandre Bouron, Jean-François Ghersi-Egea

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 418 KB

english, 2011

19

P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) Localize in the Microvessels Forming the Blood-Tumor Barrier in Ependymomas

Carole Ginguené, Jacques Champier, Said Maallem, Nathalie Strazielle, Anne Jouvet, Michelle Fèvre-Montange, Jean-François Ghersi-Egea

Journal:

Brain Pathology

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

20

Nicotine Raises the Influx of Permeable Solutes Across the Rat Blood-Brain Barrier with Little or No Capillary Recruitment

Chen, J.-L., Wei, L., Bereczki, D., Hans, F.-J., Otsuka, T., Acuff, V., Ghersi-Egea, J.-F., Patlak, C., Fenstermacher, J. D.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1995

Language:

english

File:

PDF, 477 KB

english, 1995

21

A Simple Method for Evaluation of Superoxide Radical Production in Neural Cells Under Various Culture Conditions: Application to Hypoxia

Daval, Jean-Luc, Ghersi-Egea, Jean-Fraiçois, Oillet, Jean, Koziel, Violette

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1995

Language:

english

File:

PDF, 323 KB

english, 1995

22

The role of the choroid plexus in neutrophil invasion after traumatic brain injury

Szmydynger-Chodobska, Joanna, Strazielle, Nathalie, Zink, Brian J, Ghersi-Egea, Jean-François, Chodobski, Adam

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2009

Language:

english

File:

PDF, 542 KB

english, 2009

23

Brain protection at the blood–cerebrospinal fluid interface involves a glutathione-dependent metabolic barrier mechanism

Ghersi-Egea, Jean-François, Strazielle, Nathalie, Murat, Audrey, Jouvet, Anne, Buénerd, Annie, Belin, Marie-Françoise

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2006

Language:

english

File:

PDF, 223 KB

english, 2006

24

Inducibility of rat brain drug-metabolizing enzymes

J. F. Ghersi-Egea, B. Walther, R. Perrin, A. Minn, A. Minn, G. Siest

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

1987

Language:

english

File:

PDF, 451 KB

english, 1987

25

Enzyme mediated superoxide radical formation initiated by exogenous molecules in rat brain preparations

Jean-François Ghersi-Egea, Marie-Hélène Livertoux, Alain Minn, Rachel Perrin, Gérard Siest

Journal:

Toxicology and Applied Pharmacology

Year:

1991

Language:

english

File:

PDF, 2.04 MB

english, 1991

26

Drug transfer in the choroid plexus. Multiplicity and substrate specificities of transporters

Jean-François Ghersi-Egea, Yuichi Sugiyama

Journal:

Advanced Drug Delivery Reviews

Year:

2004

Language:

english

File:

PDF, 53 KB

english, 2004

27

Detoxification systems, passive and specific transport for drugs at the blood–CSF barrier in normal and pathological situations

Nathalie Strazielle, Seng T. Khuth, Jean-François Ghersi-Egea

Journal:

Advanced Drug Delivery Reviews

Year:

2004

Language:

english

File:

PDF, 575 KB

english, 2004

28

Brain barrier systems: a new frontier in metal neurotoxicological research

Wei Zheng, Michael Aschner, Jean-Francois Ghersi-Egea

Journal:

Toxicology and Applied Pharmacology

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

29

Electronic Spin Resonance Detection of Superoxide and Hydroxyl Radicals During the Reductive Metabolism of Drugs by Rat Brain Preparations and Isolated Cerebral Microvessels

Jean-François Ghersi-Egea, Véronique Maupoil, David Ray, Luc Rochette

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 190 KB

english, 1998

30

Brain mitochondrial cytochrome P-450scc: Spectral and catalytic properties

Bernard Walther, Jean-François Ghersi-Egea, Alain Minn, Gérard Siest

Journal:

Archives of Biochemistry and Biophysics

Year:

1987

Language:

english

File:

PDF, 366 KB

english, 1987

31

Distribution of cytochrome p450 activities towards alkoxyresorufin derivatives in rat brain regions, subcellular fractions and isolated cerebral microvessels

Rachel Perrin, Alain Minn, Jean-François Ghersi-Egea, Marie-Christine Grassiot, Gerard Siest

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 735 KB

english, 1990

32

Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain

Jean-François Ghersi-Egea, Rachel Perrin, Brigitte Leininger-Muller, Marie-Christine Grassiot, Claude Jeandel, Jean Floquet, Gérard Cuny, Gérard Siest, Alain Minn

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.40 MB

english, 1993

33

Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat

J.-F Ghersi-Egea, W Finnegan, J.-L Chen, J.D Fenstermacher

Journal:

Year:

1996

Language:

english

File:

PDF, 1.20 MB

english, 1996

34

Drug metabolizing enzymes in the brain and cerebral microvessels

Alain Minn, Jean-François Ghersi-Egea, Rachel Perrin, Brigitte Leininger, Gérard Siest

Journal:

Brain Research Reviews

Year:

1991

Language:

english

File:

PDF, 2.50 MB

english, 1991

35

A new aspect of the protective functions of the blood-brain barrier: Activities of four drug-metabolizing enzymes in isolated rat brain microvessels

Jean-François Ghersi-Egea, Alain Minn, Gérard Siest

Journal:

Year:

1988

Language:

english

File:

PDF, 521 KB

english, 1988

36

Blood-brain interfaces: relevance to cerebral drug metabolism

J.F. Ghersi-egea, B. Leininger-muller, R. Cecchelli, J.D. Fenstermacher

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 931 KB

english, 1995

37

Subcellular distribution of cytochrome P-450 in the brain

B. Walther, J.F. Ghersi-Egea, A. Minn, G. Siest

Journal:

Year:

1986

Language:

english

File:

PDF, 621 KB

english, 1986

38

The activity of 1-naphthol-UDP-glucuronosyltransferase in the brain

J.F. Ghersi-Egea, B. Walther, D. Decolin, A. Minn, G. Siest

Journal:

Neuropharmacology

Year:

1987

Language:

english

File:

PDF, 592 KB

english, 1987

39

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain

Charlotte Schmitt, Nathalie Strazielle, Jean-François Ghersi-Egea

Journal:

Journal of Neuroinflammation

Year:

2012

Language:

english

File:

PDF, 1.88 MB

english, 2012

40

Prostaglandin E2metabolism in rat brain: Role of the blood-brain interfaces

Eudeline Alix, Charlotte Schmitt, Nathalie Strazielle, Jean-François Ghersi-Egea

Journal:

Fluids and Barriers of the CNS

Year:

2008

Language:

english

File:

PDF, 294 KB

english, 2008

41

Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection

Ingrid Kratzer, Shane A Liddelow, Norman R Saunders, Kate M Dziegielewska, Nathalie Strazielle, Jean-Francois Ghersi-Egea

Journal:

Fluids and Barriers of the CNS

Year:

2013

Language:

english

File:

PDF, 839 KB

english, 2013

42

Physiology of Blood–Brain Interfaces in Relation to Brain Disposition of Small Compounds and Macromolecules

Strazielle, N., Ghersi-Egea, J. F.

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.94 MB

english, 2013

43

Ethoxyresorufin O-deethylase activity in rat brain subcellular fractions

Walther, Bernard, Ghersi-Egea, Jean-François, Jayyosi, Zaid, Minn, Alain, Siest, Gérard

Journal:

Neuroscience Letters

Year:

1987

Language:

english

File:

PDF, 296 KB

english, 1987

44

Blood–brain interfaces and cerebral drug bioavailability

Ghersi-Egea, J.-F., Mönkkönen, K.S., Schmitt, C., Honnorat, J., Fèvre-Montange, M., Strazielle, N.

Journal:

Revue Neurologique

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

45

Cimetidine inhibits cerebral and hepatic mitochondrial respiration in rat

Ghersi-Egea, J.F., Sautegeau, A., Walther, B., Minn, A, Saunier, C.

Journal:

Toxicology Letters

Year:

1986

Language:

english

File:

PDF, 422 KB

english, 1986

46

Induction and immunological characterization of the uridine diphosphate-glucuronosyltransferase conjugating 1-naphthol in the rat choroid plexus

Leininger-Muller, Brigitte, Ghersi-Egea, Jean-François, Siest, Gérard, Minn, Alain

Journal:

Neuroscience Letters

Year:

1994

Language:

english

File:

PDF, 355 KB

english, 1994

47

Uridine diphosphate-glucuronosyltransferase activities in rat brain microsomes

Minn, A., Suleman, F.G., Ghersi-Egea, J.-F., Leininger-Muller, B.

Journal:

Neuroscience Letters

Year:

1993

Language:

english

File:

PDF, 365 KB

english, 1993

48

Rôles biologiques des éléments traces dans le cerveau – exemples du Zn et du Fe

Paoletti, P., Arnaud, J., Hunot, S., Boom, A., Bouron, A., Bohic, S., Ghersi-Egea, J.-F., Gibon, J.

Journal:

Revue Neurologique

Year:

2011

File:

PDF, 408 KB

2011

49

Choroid Plexus Transporters for Drugs and Other Xenobiotics

Ghersi-Egea, Jean-FranÇois, Strazielle, Nathalie

Journal:

Journal of Drug Targeting

Year:

2002

Language:

english

File:

PDF, 129 KB

english, 2002

50

The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher

Chodobski, Adam, Ghersi-Egea, Jean-François, Nicholson, Charles, Nagaraja, Tavarekere N, Szmydynger-Chodobska, Joanna

Journal:

Fluids and Barriers of the CNS

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

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